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IVA release notes

v2.12.3-1 (2025-01-10)

The currrent version comprises v2.12 and 100kGP data release 16.

Features

  • Filters History: provides a history of recent queries in Variant Browser and Case Portal. The history resets when moving to a different tool within IVA. We recommend using Save filter for longer term retention.
  • Pedigree diagram in the Case Interpreter Case Info page.
  • Variant Browser filtering by up to three sample platekeys. This will find variants in any of the samples using OR logic.
  • Additional gnomAD exomes allele frequencies.
  • Updated Case search page in the Case Interpreter. The filters have moved to a panel on the left, with only search by Proband ID (participant ID) and Sample ID (platekey) available.
  • Features and filters not available for use with current dataset removed from interface where possible.
  • Individual cases can now be launched in case interpreter from case portal in a new tab
  • Genome Browser view added to the Variant Browser and Case Interpreter Variant Browser.
  • Many minor interface changes.

Bugfixes

  • Red TypeError pop-up boxes on the Variant Browser have been resolved and no longer appear. These were as a result of trying to look up GO and HPO terms, however these were never linked to the genes in the underlying database, which caused the errors.
  • Variant browser can successfully process more complex queries.
  • Error when reloading Saved filters in Sample Browser, Individual Browser, Family Browser, Disease Panel Browser has been resolved.
  • Error when loading "last page" of search results in Case Portal and Sample Browser has been resolved.